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Home/ Compare/ CBD Paste vs CBD Oil

CBD Paste vs CBD Oil: Concentration, Base and Dosing

A CBD paste is concentrated whole hemp extract dispensed from an applicator, with the plant waxes and non-cannabinoid compounds left in. A CBD oil is the same extract diluted in a carrier oil and counted out as drops. At a matched percentage a gram of each carries the same milligrams.
No human study has compared the two formats, and no absolute oral bioavailability exists for CBD in any form.

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At a glance

Property
CBD paste
CBD oil
What it is
Thick, undiluted hemp extract with plant waxes and minor cannabinoids.
Hemp extract diluted in a carrier oil to a declared mg per ml.
How you take it
From a dosing ring: a half turn gives about 0.5 g.
Counted as drops from a pipette under the tongue.
Onset
Unmeasured: no human study has tested a hemp paste.
Peak plasma CBD came 4 hours after sublingual drops in 8 healthy males.
How long effects last
Unmeasured; CBD half life on chronic oral dosing is 2 to 5 days.
Half life was 56 to 61 hours on twice daily dosing.
Oral bioavailability
Never established for a concentrated extract or any swallowed form.
Never established; the one absolute CBD figure in humans is 31% for smoking.
Dose precision
Lower: 0.5 g of a 50% extract is about 250 mg.
Higher: 150 mg per ml gives about 5 mg per drop.
Taste and discretion
Strong, bitter and resinous; a applicator is not discreet.
Grassy and bitter, but dilutable in a drink.
THC content
A 10 g applicator must keep THC under 1 mg per component part.
The 1 mg ceiling applies to finished goods, not the extract.
Endoca product
Endoca Raw CBD oil extract, 500 mg CBD plus CBDa per ml, 50%.
Endoca CBD oil, 150 mg CBD per ml at 15%, 10 ml or 30 ml.

What actually differs

Two things: how much carrier oil was added, and whether the extract was heated. A paste is the oleoresin more or less as it leaves extraction, which is why it is thick and needs a wide bore applicator rather than a pipette. An oil is the same material let down in hemp seed oil until a drop carries a predictable milligram figure. At matched percentages the cannabinoid content per gram is identical, which is the point most comparisons miss.
Heat is the more interesting difference. In a raw extract the dominant compound is CBDa, the acid precursor, not CBD, and converting it means decarboxylating. That is not free. In hemp extracts held at 110 degrees Celsius, the sum of acid plus neutral cannabinoid measured fell by 18.05 percent on completion, rising to 25.2 percent at 130 degrees Celsius. A raw paste keeps the CBDa; a decarboxylated oil trades some total measurable cannabinoid for CBD.
What outranks both choices is food. With a high fat, high calorie meal, cannabidiol peak plasma concentration rose 5-fold and total exposure 4-fold. No paste against oil comparison in humans exists.

Where the difference actually shows up

In dose control, and the arithmetic is unforgiving. Endoca’s dosing ring releases roughly 0.5 g on a half turn. At 30 percent that is about 150 mg of CBD plus CBDa in one portion, and at 50 percent about 250 mg. A drop of 15 percent oil is about 5 mg. The two formats are not on the same scale of granularity, which is why a paste is a poor place to start and a reasonable place to end up.
In what is actually in the container. Raw extract is CBDa dominant, and CBDa is not CBD. Across dogs, cats and horses, oral CBDa reached substantially higher peak plasma concentrations than CBD at comparable doses, with roughly 3 to 7 fold higher Cmax in dogs. A 2023 review of that literature states plainly that there is a dearth of information regarding CBDa in the human literature.
And in handling. A paste is sticky, it stains, the ring needs turning with warm hands, and it tastes strongly of the plant. An oil does none of that. Those are the differences a buyer will actually notice.

What the human evidence shows

CBD paste
No human pharmacokinetic study has tested a concentrated hemp extract paste, so no Cmax or bioavailability figure exists.
No controlled human trial has compared a CBDa containing raw extract with a decarboxylated extract at the same cannabinoid dose.
In dogs, cats and horses, oral CBDa reached higher peak plasma concentrations than CBD at comparable doses, with Cmax in dogs roughly 3 to 7 fold higher.
CBD oil
In 8 healthy males, CBD oil as sublingual drops gave Cmax 24.0 ng/mL and Tmax 4 hours, indistinguishable from the same oil in capsules.
Producing the decarboxylated form has a measured cost: heating hemp extracts to 110 degrees Celsius lost 18.05 percent of total molar cannabinoid content, and 25.2 percent at 130 degrees.
No human study has established an absolute oral bioavailability for CBD in oil; a 2018 systematic review of 24 studies found none.

The gap is the comparison itself. Paste against oil has never been run in humans, so nobody can say which is better absorbed, and the CBDa advantage rests on animal data with a stated absence of human evidence. At the same percentage, a gram of each carries the same milligrams.

What people get wrong

01 Paste is stronger than oil.
Not inherently. A gram of a 30 percent paste and a gram of a 30 percent oil carry the same 300 mg. Paste reaches higher, up to 50 percent, but texture is not strength.
02 Raw CBD paste gives you more CBD.
It gives you less. Raw extract is mostly CBDa, the acid precursor, a different compound with different receptor behaviour. A decarboxylated extract is the one that contains CBD.
03 Decarboxylating just flips CBDa into CBD with nothing lost.
Measurably not. Heating hemp extracts to 110 degrees Celsius lost 18.05 percent of the total molar concentration of acid plus neutral cannabinoid, and 130 degrees Celsius lost 25.2 percent.

Choosing between them

Start on oil and move to paste only if the arithmetic calls for it. A dropper at about 5 mg per drop lets you work in small steps; an applicator ring at 250 mg a half turn does not. Once a daily amount is settled and counting drops has become tedious, the paste holds the same milligrams in less volume. Choose raw against decarboxylated on what is in the container rather than on the word: raw extract is CBDa dominant and standard extract is CBD dominant, and those are different compounds.

How Endoca tests for this

For these two formats the certificate of analysis matters most, because it is the only way to tell a raw extract from a decarboxylated one. Endoca’s batch COAs report CBD and CBDa separately, alongside minor cannabinoids, total THC, pesticides, heavy metals, residual solvents and microbes. What a COA cannot tell you is how much you will absorb, because that has not been established for CBD in humans by any route except smoking. Endoca works from its own farm, own land and own extraction, since 2010.

Frequently asked questions

Not by format. Strength is the percentage, or the milligrams per gram, and a 30 percent paste and a 30 percent oil carry identical content per gram. Paste does reach higher at the top of the range, up to 50 percent.

Heat. Raw extract is unheated and dominated by CBDa, the acid precursor. Regular extract has been decarboxylated, converting CBDa into CBD. They are different compounds, not different grades, and a certificate of analysis reporting them separately is how you tell them apart.

Work in milligrams, not turns. The dosing ring releases about 0.5 g on a half turn and 1 g on a full turn, so a 30 percent extract gives roughly 150 mg per half turn. Calculate before dispensing, not after.

In animals, yes. Oral CBDa reached roughly 3 to 7 fold higher peak plasma concentrations than CBD in dogs, with similar patterns in cats and horses. A 2023 review of that work states there is a dearth of information on CBDa in the human literature.

References

01

Millar SA, Stone NL, Yates AS, O’Sullivan SE. A systematic review on the pharmacokinetics of cannabidiol in humans. Front Pharmacol. 2018;9:1365.

02

Wang M, Wang YH, Avula B, et al. Decarboxylation study of acidic cannabinoids: a novel approach using ultra-high-performance supercritical fluid chromatography/photodiode array-mass spectrometry. Cannabis Cannabinoid Res. 2016;1(1):262-271.

03

Schwark WS, Wakshlag JJ. A One Health perspective on comparative cannabidiol and cannabidiolic acid pharmacokinetics and biotransformation in humans and domestic animals. Am J Vet Res. 2023;84(5):ajvr.23.02.0031.

04

Johnson DA, Funnell MP, Heaney LM, et al. Cannabidiol oil ingested as sublingual drops or within gelatin capsules shows similar pharmacokinetic profiles in healthy males. Cannabis Cannabinoid Res. 2024;9(5):e1423-e1432.

05

Williams NNB, Ewell TR, Abbotts KSS, et al. Comparison of five oral cannabidiol preparations in adult humans: pharmacokinetics, body composition, and heart rate variability. Pharmaceuticals (Basel). 2021;14(1):35.

06

Epidyolex 100 mg/ml oral solution. Summary of product characteristics, sections 4.2 and 5.2. Jazz Pharmaceuticals.

07

Food Standards Agency and Food Standards Scotland. Food Standards Agency and Food Standards Scotland update consumer advice for CBD, 12 October 2023.

08

Regulation (EU) 2015/2283 on novel foods, as retained in Great Britain law.

09

The Misuse of Drugs Regulations 2001, SI 2001/3998, regulation 2(1), definition of exempt product.

Last reviewed 1 October 2026.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.