Science Direct lists a paper that was published in the journal Neuropharmacology describing a study on the rapid-acting antidepressant-like effects of CBD on the olfactory bulbectomy mouse model of depression (OBX).
Depression, although a very common condition, is not very well understood by medical science. It is more than just feeling down, or having a dark cloud hanging over your head. It is a state many people spend years of their lives in, and it colors everything, leaving life feeling like too much of an effort to live.
It has a certain stigma attached as a “mental condition” and can be seen as shameful. To some it means failure to cope. If they had to admit they are depressed on top of all else, it would only add to their despair.
Antidepressant medications are not the most cheerful of treatments. They are well documented as being risky and riddled with side effects. The FDA warns against increased risk of suicide as a serious side effect to consider, especially in young adults. Other side effects include; nausea, anxiety, weight gain, tremors, hives and sweating to name but a few. And you have to keep on taking these drugs. They can take weeks or months to work if they work at all.
If patients decide to stop taking antidepressants it is essential to consult a doctor, and taper off slowly, as withdrawal symptoms could be difficult to cope with. These are really scary drugs.
A selection of our products
A chemical imbalance
It is a common belief that depression is caused by a chemical imbalance in the brain, or serotonin shortage. Mental health researchers disagree, and are discovering that the causes of depression are much more complex than the chemical imbalance theory suggests.
They are starting to look into factors such as inflammation, elevated stress hormones, immune system suppression, nutritional deficiencies, and abnormal activity in certain parts of the brain, or shrinking brain cells to name a few possible biological causes. Social and psychological factors also play an enormous role.
Cannabidiol (CBD) is poorly explored as a treatment for depression
Cannabidiol (CBD), the major non-psychoactive component found in cannabis, showed anti-anxiety properties in many behavioral tests, yet its potential as a treatment for depression, has not been explored. The mechanism of action of CBD also remains unclear.
The recent study evaluated the effects of CBD administration in the olfactory bulbectomy mouse model of depression (OBX) to investigate the underlying mechanism.
Researchers concluded that their findings demonstrate that CBD exerts “fast and sustained antidepressant-like effects.” They added that CBD could represent a novel and fast working antidepressant drug by enhancing both serotonergic and glutamate cortical signaling through a 5-HT1A receptor-dependent mechanism.
In short: CBD oil for depression
CBD oil for depression could be another “wonder cure”. It is unbelievable how many benefits this cannabinoid holds, but then again, if it is true that it restores balance to the body, it does make a lot of sense that it could bring the solution to many conditions caused by imbalances.