PR Newswire looks into the use of cannabidiol to overcome addiction and other unmet medical needs.
Pharmaceutical companies look into CBD for addiction to nicotine
Nicotine addiction is still the most prevalent of all addictions. Nicotine is also one of the most addictive substances known to mankind. Once is usually one time too many, as most people are then addicted for life.
Medical science has come up with cures and answers to very many ailments and health problems. As we know our life expectancy is on the rise decade on decade, but addiction still goes unsolved, and smoking cessation is a big market.
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Smoking becomes unacceptable
It has become somewhat socially unacceptable to smoke cigarettes, and smoking is prohibited in most public places in most countries around the world.
Apart from sneaking off around corners where smokers are safe from the scornful glare of non-smokers or keeping the habit contained in the privacy of their own homes, smokers are turning to “smokeless” tobacco according to research.
Chewing tobacco and snuff
Statista displays the statistics for sales of smokeless tobacco products in U.S. convenience stores in 2015, finding that chewing tobacco and snuff generated approximately 5.93 billion U.S. dollars. The total category sales generated about 6.18 billion U.S. dollars.
But what if a substance other than nicotine could make quitting easier? This is why companies are looking into possible solutions, and nicotine replacement products.
Big Pharma knows the value of this market all too well as Pfizer can clearly confirm with the blockbuster drug, Chantix, generating $672 million in 2015. Pfizer successfully capitalized on an unmet need.
Most of these nicotine replacement therapy drugs (NRTs) such as Zyban and Chantix, approved by the FDA have their dangers and come with “black box” warnings. This is why companies such as CV Sciences, Inc. (CVSI) are looking into chewing gum combining synthetic CBD with nicotine to treat smokeless tobacco and tobacco addiction.
The gum meets the three requirements for treating nicotine addiction. CBD inhibits monoamine oxidase to replace tobacco alkaloids, and provides an antidepressant effect. Secondly, small doses of nicotine in the gum address the nicotine addiction and craving, and thirdly the chewing of the gum provides oral stimulation.
CEO of CVSI is confident CVSI-007 gum is a winner as he said there are no FDA-approved drugs to treat smokeless tobacco addiction. The FDA has approved numerous NRTs, and he believes this candidate will be extremely well received in the market as the FDA has recent experience with CBD, and this will accelerate the drug development process and approval.
CBD medicine to quit: should it contain nicotine?
The problem with replacing nicotine with nicotine products is quite obvious: the addiction is not dealt with, and the addict is just using a different product. CBD for addiction could be a successful remedy, but is it necessary to synthesize the compound, and then add nicotine to it, or would the whole plant extract in a natural state provide a sounder solution?