Parkinson’s disease is a neurodegenerative disease, and has no effective conventional treatment. Most treatment drugs increase dopamine, which have neurotoxic side effects, effectively speeding up the neurodegenerative effect of the disease.
The need for a natural, effective and safe medicine, which is backed by scientific research, is urgent. Two preclinical studies on PD animal models to assess the neuroprotective properties of CBD revealed highly promising results. The Waking Times recently placed an article on cannabinoids for Parkinson’s disease (PD).
The results of the first study published by Lastres-Becker et al showed that the antioxidant effects of CBD had counteracted neurodegeneration. The next year, the same team of scientists found that acute administration of CBD seemed to have a neuroprotective action.
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In addition to these two animal studies, three human clinical trials were conducted on the neuroprotective effects of cannabidiol. It was discovered that the region in the brain with the highest prevalence of CB1-receptors is also the target area of neurostimulation in patients with Parkinson’s disease who developed tremors.
Positive effects of CBD on this region in the brain were shown by MRSI results. The conclusion was made that it may be worth testing the influence of CBD cannabinoid in the onset of Parkinson’s disease.
A second study looked into cannabidiol as treatment of psychosis in Parkinson’s disease. It assessed the therapeutic use and neuroprotective effect of cannabidiol in PD patients. The results of the study showed significant improvement of psychosis as well as general symptoms in PD patients.
The third study looked into the effects of cannabidiol in the treatment of patients with Parkinson’s disease. An increase in quality of life and well-being was observed in patients receiving the higher dose of cannabidiol versus the placebo groups. The conclusion made by the group of researchers is that improvements might be due to the anxiolytic, antidepressant, sedative and anti-psychotic properties of cannabidiol. These results indicate CBD may provide a powerful drug alternative for PD.
The National Parkinson’s Foundation begs to differ: or does it?
Sadly the foundation chooses to quote an article published by the National Institute on Drug Abuse (NIDA) Director Dr. Nora Volkow. In the article she carefully outlined the adverse health effects of marijuana use. Yet again, the focus is placed on the THC cannabinoid in marijuana while all the above-mentioned studies were conducted on the CBD cannabinoid.
Cannabinoids for Parkinson’s: it depends which one you look at
The cannabinoid currently being considered for the treatment of Parkinson’s is clearly cannabidiol or CBD obtained from the oil in the cannabis plant more generally known as industrial hemp. Hemp contains as little as 0.3% THC. You could compare CBD oil fears to saying “Don’t eat poppy seed muffins, they contain opium!”